If patients do not respond adequately to the maximal dose of Amaryl monotherapy, addition of metformin may be considered. Published clinical information exists for the use of other sulfonylureas including glyburide, glipizide, chlorpropamide, and tolbutamide in combination with metformin.
With concomitant Amaryl and metformin therapy, the desired control of blood glucose may be obtained by adjusting the dose of each drug. However, attempts should be made to identify the minimum effective dose of each drug to achieve this goal. With concomitant Amaryl and metformin therapy, the risk of hypoglycemia associated with Amaryl therapy continues and may be increased. Appropriate precautions should be taken.
Most important information about Amaryl
More information about AMARYL (Glimepiride):
Amaryl-Insulin Combination Therapy
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Tags: Amaryl (Glimepiride), Conditions & Treatments, Medications, Type 2 Diabetes
i, vijaybhaskar,33 yrs, am a known diabetic since 1 year . iam using metformin 500mg+glimepiride 1mg since 6 months.my sugar levels are completely normal. i want to reduce my dosage levels.is it possible.