What is the most important information I should know about Glucophage (Metformin)?
A small number of people who have taken metformin have developed a serious condition called lactic acidosis that has been fatal in up to 50% of cases. Lactic acidosis has occurred most often in people whose kidneys were not working properly. Liver problems may also increase the risk of developing lactic acidosis. Stop taking metformin and call your doctor immediately if you experience a feeling of general discomfort or sickness; weakness; sore or aching muscles; trouble breathing, unusual drowsiness, dizziness or lightheadedness; unusual or unexplained stomach upset (after the initial stomach upset that may occur at the start of therapy with metformin); or the sudden development of a slow or irregular heartbeat. These may be signs of lactic acidosis.
Avoid excessive alcohol intake while taking metformin. Together, alcohol and metformin may increase the risk of lactic acidosis and hypoglycemia.
Metformin does not usually cause hypoglycemia (low blood sugar). Nevertheless, hypoglycemia may occur in the treatment of diabetes, as a result of skipped meals, excessive exercise, or alcohol consumption. Know the signs and symptoms of low blood sugar, which include hunger, headache, drowsiness, weakness, dizziness, a fast heartbeat, sweating, tremor, and nausea. Carry non-dietetic candy or glucose tablets to treat episodes of low blood sugar.
What should I discuss with my doctor before taking Glucophage (Metformin)?
Do not take metformin without first talking to your doctor if you
- have kidney disease;
- have liver disease;
- have congestive heart failure;
- have acute or chronic metabolic acidosis, including diabetic ketoacidosis;
- have had a heart attack or a stroke;
- have a serious infection, illness, or injury;
- need to have surgery;
- need to have x-rays or other procedures using injectable contrast agents;
- are dehydrated (have lost water from your body) due to diarrhea, vomiting, fever, heat stroke, decreased fluid intake, or any other cause;
- drink alcohol; or
- are 80 years of age or older and have not had your kidney function tested.
You may not be able to take metformin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Contact your doctor if you develop a fever or an infection, require surgery, or if you experience a serious injury. Illness or injury may cause a loss of blood sugar control and insulin (or an adjustment of a current insulin dose) may be required for a period of time.
Metformin is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Generally, insulin is the drug of choice for controlling diabetes during pregnancy. Do not take metformin without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Metformin passes into breast milk and may affect a nursing baby. Do not take metformin without first talking to your doctor if you are breast-feeding a baby.
If you are over the age of 65 years, there may be an slight increase in the risk of developing lactic acidosis due to a natural decline in kidney function with advancing age. A lower dose or special monitoring may be necessary during your treatment.
More information about Glucophage (Metformin):
Cancer Benefit for Diabetes Drug Glucophage
Kidney Fund concerned about Glucophage fatality risk
FDA approves new indication for Glucovance oral antidiabetic
For more information look HERE: My Family Drugstore
Tags: Conditions & Treatments, Glucophage (Metformin), Medications, Type 2 Diabetes